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The
name LASER is an acronym for Light Amplification by the
Stimulated Emission of Radiation. In 1917, Albert
Einstein first theorized about the process which makes lasers possible
called "Stimulated Emission."
In
1954, Charles Townes and Arthur Schawlow invented the maser (microwave
amplification by stimulated emission of radiation),
using ammonia gas and microwave radiation - the maser was invented before
the (optical) laser. The technology is very close but does not use a visible
light.
In
1958, Charles Townes and Arthur Schawlow theorized about a visible laser, an
invention that would use infrared and/or visible spectrum light.
Theodore Maiman
invented the ruby laser considered to be the first successful optical or
light laser. Gordon Gould was the first person to use the word "laser".
Gould was a doctoral student at Columbia University under Charles Townes,
the inventor of the maser. Gordon Gould was inspired to build his
optical laser starting in 1958. He failed to file for a patent his
invention until 1959. As a result, Gordon Gould's patent was refused and
his technology was exploited by others. It took until 1977 for Gordon
Gould to finally win his patent war and receive his first patent for the
laser.
The
History of Medical Lasers
Light Amplification
by the Stimulated Emission
of Radiation
was originally described as a theoretical concept by Albert Einstein in
1917, but it was not until 1954 that the first "stimulated" emissions of
microwave radiation (MASER)
were generated by J.P. Gordon and C.H. Townes at Bell Laboratories.
Theoretical calculations for the construction of a visible light MASER, or
LASER were published in 1958. The first
LASER was built in 1960 by Dr. T.H. Maiman at
Hughes Aircraft Company, using a synthetic ruby rod stimulated by high
intensity flashlamps, which generated millisecond pulses of coherent 694nm Ruby Laser (red)
light . Shortly afterwards, 1060nm (near-infrared)
laser light was generated by stimulating glass rods doped with Neodymium (Nd:Glass
Laser).
Within a year, pioneers such as Dr. Leon Goldman began research on the
interaction of laser light on biologic systems, including early clinical
studies on humans. Interest in medical applications was intense, but the
difficulty controlling the power output and delivery of laser energy, and
the relatively poor absorption of these red and infrared wavelengths led to
inconsistent and disappointing results in early experiments. The exception
was the application of the Ruby Laser
in retinal surgery in the mid-60's. In 1964, the
Argon Ion Laser
was developed. This continuous wave 488nm (blue-green)
gas laser was easy to control, and it's high absorption by hemoglobin made
it well suited to retinal surgery, and clinical systems for treatment of
retinal diseases were soon available.
In 1964,
the Nd:YAG (Neodymium:Yttrium
Aluminum Garnet) Laser and
CO2
(Carbon Dioxide)
Laser
were developed at Bell Laboratories. The CO2 laser is a continuous wave gas
laser, and emitted infrared light at 10600nm in an easily manipulated,
focused beam that was well absorbed by water. Because soft tissue consists
mostly of water, researchers found that a CO2 laser beam could cut tissue
like a scalpel, but with minimal blood loss. The surgical uses of this laser
were investigated extensively from 1967-1970 by pioneers such as Dr. Thomas
Polanyi and Geza Jako, and in the early 70's, use of the CO2 laser in ENT
and gynecologic surgery became well established, but was limited to academic
and teaching hospitals.
Dye
Lasers
became available in 1969, and noble gas-halide, or Excimer Lasers
in 1975. Since then, many other different laser systems have
become available for industrial scientific, telecommunication, as well as
medical use.
In the
early 1980's, smaller but more powerful lasers became available, and were
soon appearing in community hospitals and even physician's offices. Most of
these systems were CO2 lasers used for cutting and vaporizing, and Argon
lasers for ophthalmic use.
Nd:YAG
and KTP
laser systems were used by larger hospitals for the new field of
laparoscopic surgery. These "second generation" lasers were all continuous
wave, or CW systems, which tend to cause non-selective heat injury, and
proper use required a long "learning curve" and experienced laser surgeons.
The single
most significant advance in the use of medical lasers was the concept of
"pulsing" the laser beam, which allowed selective destruction of abnormal or
undesired tissue, while leaving surrounding normal tissue undisturbed. The
first lasers to fully exploit this principal of "selective thermolysis" were
the
Pulsed Dye Lasers
introduced in the late 1980's for the treatment of port wine stains and
strawberry marks in children, and shortly after, the first
Q-switched lasers
for the treatment of tattoos. Another major advance was the introduction of
scanning devices in the early 1990s, enabling precision computerized control
of laser beams. Scanned, pulsed lasers revolutionized the practice of
plastic and cosmetic surgery by making safe, consistent laser resurfacing
possible, as well as increasing public awareness of laser medicine and
surgery.
Medical lasers have made it
possible to treat conditions which previously were untreatable, or difficult
to treat. Patients benefit by improved results and less cost. In the last
few years, the main focus of research and development of medical lasers has
been on Laser Hair Removal , the treatment of vascular lesions including Leg
Veins, and vision correction. The thrust of current research is directed
towards non-ablative laser resurfacing ("laser skin toning"), "no-touch"
computerized vision correction, and improved photodynamic therapy for
treatment of skin cancer and for hair removal.
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